Chapter 12

Presbyvestibulopathy

Age-related decline of the vestibular system. Mild, symmetric, slow, and unmistakably real — the older patient's chair report is rarely entirely normal.

Clinical picture

The Bárány Society defines presbyvestibulopathy as a chronic vestibular syndrome in older adults (typically ≥ 60 years) with symptoms of postural imbalance or fall(s), and mild bilateral peripheral vestibular dysfunction documented on testingAgrawal Y 2019. Symptoms are slow, symmetrical, and non-episodic.

Pathophysiology

Type I hair-cell loss accelerates after age 60, and afferent nerve-fibre counts decline; the cupula stiffens slightly. The net effect is a low-frequency reduction in VOR drive, with the highest frequencies preserved.

RCT pattern

Gain · eye / chair00.601.200.010.020.040.080.160.320.64frequency (Hz, log)Phase lead · degrees-2030800.010.020.040.080.160.320.64frequency (Hz, log)Symmetry · %-500500.010.020.040.080.160.320.64frequency (Hz, log)
Three-panel SHA summary. Shaded green = published normal band. Solid marker = patient/archetype curve; dashed = overlaid reference if shown.
Reduced VOR gain
Step Tc14.0 s
Step gain0.65

The earliest change is reduced gain at the lowest SHA frequencies (0.01–0.04 Hz), with progressively spared gain through 0.16–0.64 Hz Wang Y 2022. The post-rotational Tc drifts downward before the per-rotational. Phase and symmetry are usually preserved until very late.

Diagnosis & differential

  • RCT consistent with the age-related pattern above.
  • vHIT showing borderline gains, often with covert saccades.
  • cVEMP and oVEMP frequently reduced bilaterally.
  • Distinguish from frank bilateral vestibulopathy (gain < 0.1 criterion) and from cerebellar ataxia in the older patient.