Module 04

Normal Waveforms

An interactive laboratory for the normal cVEMP and oVEMP. Move the sliders, compare sides, and watch the interaural asymmetry ratio update live.

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Foundation

The two diagnostic peaks

Every clinical VEMP is described by two peaks. For the cVEMP, an initial positive peak called P1 (or p13) is followed by a negative peak N1 (n23). The oVEMP reverses that order — N1 first at about 10 ms, then P1 at about 16 ms.

Try the simulator below. Toggle between cVEMP and oVEMP and notice how the peaks change.

01020304050Time (ms)+1000100Amplitude (µV)P1N1Left ear (110 µV)Right ear (95 µV)
Interaural Asymmetry Ratio
7.3%
Within normal limits (< 33%)
Trainee

Normative ranges

cVEMPoVEMP
P1 latency~13 ms (±1.2)~16 ms (±1.3)
N1 latency~23 ms (±2.0)~10 ms (±1.0)
P1–N1 amplitude60–200 µV4–15 µV
Threshold75–95 dBnHL90–105 dBnHL
Best frequency500 Hz500 Hz
IAR upper limit33–40 %33–40 %

The interaural asymmetry ratio (IAR)

The IAR adapts the Jongkees caloric formula to VEMP amplitudes:

IAR = ( |L − R| / (L + R) ) × 100

Values under 33% are considered symmetric in most labs; 33–40% is a grey zone; above 40% suggests genuine asymmetry of otolith function. The simulator above computes the IAR live as the amplitude sliders change.[1,2]

Clinician

A worked example

A 40-year-old presents with right-sided fullness and a single attack of vertigo. cVEMP amplitudes are recorded at 120 µV on the left and 55 µV on the right. Plug those values into the IAR:

IAR = (|120 − 55| / (120 + 55)) × 100 = (65 / 175) × 100 ≈ 37.1%

That value is in the borderline range — within laboratory tolerance for some norms but flagging an emerging asymmetry. Repeating at 1 kHz to check for a frequency-tuning shift would be a natural next step in this patient given the clinical suspicion of Ménière's.[8]

Threshold testing

Threshold is determined by descending the stimulus intensity in 5 dB steps until the response disappears. A pathologically low threshold (≤ 70 dBnHL on cVEMP) is the most specific finding for superior canal dehiscence; conversely, an elevated threshold can help distinguish age-related decline from focal pathology.[9]