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Physiologic

Optokinetic nystagmus (OKN)

Physiologic — striate cortex + brainstem OKN pathway

Live animation
Gaze directionprimary
← 40° LEFTPRIMARY40° RIGHT →

Slide to test Alexander's law (peripheral), gaze-evoked patterns, or the null zone (congenital).

Position-over-time tracing
HORIZ← L R →VERT↓D U↑TORS← CCW CW →

Live strip-chart. Horizontal, vertical, and torsional channels.

In a sentence

Reflexive jerk nystagmus elicited by a moving full-field visual stimulus (e.g., striped drum). Slow phase tracks the stimulus, fast phase resets.

Clinical pearls
  • Tests cortico-subcortical visual-motor pathway integrity.
  • Asymmetric OKN (one direction reduced) localizes to deep parietal/occipital cortex.
  • Absent OKN with intact pursuit suggests cortical lesion; reversed OKN occurs in congenital nystagmus.
  • Useful for malingering screen (OKN is reflexive).
Common associations
  • Normal reflex
  • Parietal lesion (asymmetric OKN)
  • Congenital nystagmus (inverted OKN)